## Rule:
Disruption in a high-connectivity hub propagates more widely and more persistently than disruption in a peripheral process. Address the hub before addressing downstream effects.
## Deriviation:
The three spirit hubs — natural (hepatic), vital (cardiac/autonomic), animal (nervous system) — are the organism's highest connectivity regulatory nodes.
## Clinical Implication:
When a presenting symptom is a downstream effect of a disrupted hub, address the hub is the primary intervention. Treating downstream effects without addressing the hub, produces temporary improvement followed by recurrence, because the hub's dynamics continue to generate downstream effects.
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